The National Academies: What You Need To Know About Infectious Disease

The National Academies

What You Need To Know About Infectious Disease

The Infectious Etiology of Chronic Diseases: Defining the Relationship, Enhancing the Research, and Mitigating the Effects—Workshop Summary (2004)

In recent years, a number of chronic diseases have been linked, in some cases definitively, to an infectious etiology: peptic ulcer disease with Helicobacter pylori, cervical cancer with several human papillomaviruses, Lyme arthritis and neuroborreliosis with Borrelia burgdorferi, AIDS with the human immunodeficiency virus, and liver cancer and cirrhosis with hepatitis B and C viruses, to name a few. The proven and suspected roles of microbes does not stop with physical ailments; infections are increasingly being examined as associated causes of or possible contributors to a variety of serious, chronic neuropsychiatric disorders and to developmental problems, especially in children.

The Infectious Etiology of Chronic Diseases: Defining the Relationship, Enhancing the Research, and Mitigating the Effects, summarizes a two-day workshop held by the Institute of Medicine’s Forum on Microbial Threats to address this rapidly evolving field. Participants explored factors driving infectious etiologies of chronic diseases of prominence, identified difficulties in linking infectious agents with chronic outcomes, and discussed broad-based strategies and research programs to advance the field.

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What do you know about infectious disease?

True or False: Infection with a pathogen (a disease-causing microbe) does not necessarily lead to disease.

  • Correct!

    Infection occurs when viruses, bacteria, or other microbes enter your body and begin to multiply. Disease follows when the cells in your body are damaged as a result of infection, and signs and symptoms of an illness appear.

  • Sorry, that’s incorrect.

    Infection occurs when viruses, bacteria, or other microbes enter your body and begin to multiply. Disease follows when the cells in your body are damaged as a result of infection, and signs and symptoms of an illness appear.